| abstract |
The present invention is related to an antibody component that binds with the HLA-DR-complex for use in a method for inducing humoral and cellular immune responses in a mammal against a tumor that expresses a tumor associated antigen (TAA) or against a disease caused by an infectious agent, said method comprising: n(a) administering a first vaccine intradermally to the mammal, wherein said first vaccine comprises an immunoconjugate that comprises: n(i) the antibody component that binds with the HLA-DR-complex, and n(ii) an antigenic peptide, wherein said antigenic peptide comprises at least one epitope of a TAA or an antigen associated with said infectious agent, n nand n(b) administering said vaccine intravenously to said mammal. |