| abstract |
The invention relates to a method of covering a metal or inorganic substrate by a molecular functionalization layer, characterized in that it comprises the following successive steps: a) prior oxidation of the surface of the substrate if it is not already at least partially hydroxylated so as to arrange hydroxyl functions on the surface of the substrate, b) contact of the surface of the substrate with a liquid, gaseous or supercritical coating composition containing gem-bisphosphonic compounds, and/or their toxicologically acceptable salts, until self-assembly of said gem-bisphosphonic compounds in a layer covering said surface, c) removal of said liquid, gaseous or supercritical coating composition, d) dehydration of the surface thus covered; the substrate recovered capable of being obtained from this method, uses of this functionalized substrate, gem-bisphosphonic compounds that can use this coating method, and uses of these gem-bisphosphonic compounds. |