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publicationDate 2009-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2050069-A2
titleOfInvention System and method for co-registering multi-channel images of a tissue micro array
abstract A system and methods for co-registering multi-channel images of a tissue micro array, comprising the steps of, providing a biological material on a substrate; applying one or more molecular probes, adapted to provide fluorescent molecular markers, to the biological material; obtaining a first digital image of the biological material and the fluorescent molecular markers; applying a morphological stain to the biological material; obtaining a second digital image of the biological material, computing information common to the first and second images; and co-registering the second image with the first image based on one or more registration metrics.
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