Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
filingDate |
2007-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a91f0c3943ae4c5d4d823b6b9e459c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b32b606d5f1a4fb68e91bcf731638f6 |
publicationDate |
2009-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2049137-A2 |
titleOfInvention |
Salicylanilides enhance oral delivery of therapeutic peptides |
abstract |
This invention pertains to the surprising discovery that salicylanilides, e.g., niclosamide and/or niclosamide analogues when orally administered in conjunction with a peptide pharmaceutical (e.g., a class A amphipathic helical peptide as described herein) significantly increases the bioavailability of that peptide. Methods of peptide delivery using such 'delivery agents' and pharmaceutical formulations are provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11419834-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3967312-A1 |
priorityDate |
2006-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |