http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2046326-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a89514464d02d75ef2065a449fb0e617 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 |
| filingDate | 2007-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73ec9e6ff1dbde305859856e58a1adb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d3b53f734cc3d4e145722e040c4c257 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b58e7dc398da79c0f3a72dafbc9d41fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23025d069f8eb46b4c5062025dba493 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5987d61cde054bd56381b129da569360 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07da0741138df0e3014c2ad3d1f1e2a7 |
| publicationDate | 2009-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2046326-A2 |
| titleOfInvention | Annellated pyrrole compounds for cancer management |
| abstract | The present invention relates to the use of annellated pyrrole compounds and in particular ML3000 (licofelone), salts or derivatives thereof, for cancer management, and in general to the use of a compound of Formula (I): wherein the variables have the meanings given in the present description, for the prevention and/or treatment of neoplasia, in particular neoplasia selected from the group consisting of papilloma, carcinoma, adenoma and adenocarcinoma, e. g. human airway or colorectal carcinoma, preferably fast-growing, multidrug resistant and/or COX-2 negative neoplasia. The invention further relates to pharmaceutical compositions for the aforesaid purposes, comprising annellated pyrrole compounds and in particular ML3000 (licofelone), optical isomers, salts or derivatives thereof, as well as to a method of treating and/or preventing neoplasia and/or restoring the ability to undergo apoptosis in a cell having lost the same. This treatment ameliorates, diminishes, actively treats, reverses or prevents any disease related to insufficient apoptosis, in particular neoplasia, and it may be combined with irradiation, heating and treatment with a cytotoxic agent for preventive and/or curative purposes. |
| priorityDate | 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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