| abstract |
Disclosed is a method for preparing a compound of Formula 1 by contacting compound of Formula 2 with R1-NH2 in the presence of a carboxylic acid and a method for preparing a compound of Formula 2 by contacting a compound of Formula 4 with phosphorus tribromide. ( 1, 2, 4 ) wherein R1 is H, C1_C4 alkyl, cyclopropyl, cyclopropylmethyl or methylcyclopropyl; R2 is CH3 or C1; R3 is C1_C6alkyl or C3_ C6 alkenyl, each optionally substituted with up to 3 halogen and up to 1 phenyl; and X is C1 or Br. Also disclosed is a method for preparing a compound of Formula 5, wherein R4, R5, R6 and Z are as defined in the disclosure, using a compound of Formula 1 that is characterized by preparing the compound of Formula 1 by the method above. |