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publicationDate 2011-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2041177-B1
titleOfInvention High affinity antibodies to human il-6 receptor
abstract A human antibody or an antigen-binding fragment which binds human IL-6 receptor (hlL-6R) with a KD of about 500 pM or less and blocks IL-6 activity with an IC50 of 200 pM or less. The antibody or antibody fragment binds hlL-6R with an affinity at least 2-fold higher relative to its binding to monkey IL-6R.
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