http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2035441-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c57f1ab8eeb456235fa24732ca373ebc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-714 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-714 |
| filingDate | 2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5728c92bc830dd7db3e0163495f64808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e5c486d18a0bba6324d57a0d3523db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_443a9f08dfb3c8cfd8d37dc9dae47bb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f45eda2f4221f1ba661de02a92a59463 |
| publicationDate | 2009-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2035441-A1 |
| titleOfInvention | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery |
| abstract | A stable pharmaceutical aqueous solution of cyanocobalamin comprised of cyanocobalamin and water wherein said solution of cyanocobalamin is suitable for intranasal administration, has a viscosity less than about 1000 cPs, and yields a bioavailability of cyanocobalamin when administered intranasally of at least about 5% relative to an intramuscular injection of cyanocobalamin. The present invention is also directed towards a method for elevating the vitamin B 12 levels in the cerebral spinal fluid (CSF) comprising administering intranasally a sufficient amount of a cyanocobalamin solution so as to increase the average ratio of vitamin B 12 in the CSF to that in the blood serum (B12 CSF/B12 Serum x 100) to at least about 1.1 comprising intranasally administering an aqueous solution of a cyanocobalamin, wherein said solution of cyanocobalamin has a bioavailability of at least 5% relative to an intramuscular injection of a cyanocobalamin. |
| priorityDate | 2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.