abstract |
The invention provides compounds of formula (I) radiolabelled with <SUP>18</SUP>F, <SUP>123</SUP>I, <SUP>76</SUP>Br, <SUP>124</SUP>I or<SUP>75</SUP>Br and salts thereof, and a method of imaging translocator protein (18kDa) (TSPO) in a subject comprising administering a compound of formula (I) radiolabelled with <SUP>18</SUP>F, <SUP>123</SUP>I, <SUP>76</SUP>Br, <SUP>124</SUP>I or <SUP>75</SUP>Br or a pharmaceutically acceptable salt thereof. The invention further provides fluoro-substituted compounds of formula (II) and salts thereof, and a method of treating a neurodegenerative disorder, inflammation or anxiety in a subject comprising administering a compound of formula (II) or a pharmaceutically acceptable salt thereof. |