http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2026782-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C11-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-09 |
| filingDate | 2007-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2081a8c46a2e2943daa5bcd16d26f381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5be2584040e1afa04530191019dd081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de70118ca6c6b696aa718db6bff51e71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d91238b8a910dfcd28c14aa821d6c77c |
| publicationDate | 2009-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2026782-A2 |
| titleOfInvention | N1,n4-bis(buta-1,3-dienyl)butane-1,4-diamine pharmaceutical compositions and uses thereof |
| abstract | N1,N4-bis(buta-1,3-dienyl)butane-1,4-diamine dihydrochloride (also referred to as MDL 72,527 and N,N'-di-2,3-butadienyl-1,4-butanediamine dihydrochloride), or salts or solvates thereof, its use as an antioxidant, its use in preventing and/or treating prostate cancer in male humans, and its use in reducing the concentration of reactive oxygen species in human prostate gland tissue or any other body tissue, and methods of making the compound thereof. Other methods include inhibiting acetyl polyamine oxidase in human prostate tissue or other human body tissue comprising administering a therapeutic amount of N,N'-bis(2,3-butadienyl)-1,4-butanediamine or a salt or solvate thereof to the human, and a method of determining oxidative stress in human prostate tissue or other human or animal body tissue comprising measuring a ratio of oxidized 2',7'-dichlorodihydrofluorescein diacetate fluorescence :DNA fluorescence and hydroethidine dye fluorescence ex vivo or in vivo. |
| priorityDate | 2006-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 314.