| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53877e6bc8dc204b647d8908c4292cc1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 |
| filingDate |
2007-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46135d9c9d498a527e9f7063a7ebe1d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f82de3d34fbf3877bf86a963d5babf3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_080d212e7ea929859ac84ec3de4a39e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f0044a14b4325ae2ef4394a4777bad1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61ea93ea2007de6eb2afae23f1c2aa7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4c201da7d4cbf02769246adeaf0b903
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e6faaadebfa9a7fc2d9cd4dba53e225
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac7f6ad04ae5a51fca3a57516d32bcad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49688291776e91c2c5f3696454afb3cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1d79d6a6bfe922aeeee1caf0195d9d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0469b94526558ffced9a85c04441d49b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6632ec41be7ba1d021d6c9abceef2055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92c38f5ed9da570716c853e6aa46dcfc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_988c444feab67b9cf7d1079cfe77c05e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b9408927bda485af9bf89fef35a9a9f |
| publicationDate |
2009-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2021461-A2 |
| titleOfInvention |
Test systems for transporter proteins |
| abstract |
The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane. |
| priorityDate |
2006-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |