Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0781 |
filingDate |
2007-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73b4f11ebe7e498bfbc6d6b29cf1869e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33269db7340dfa903ea5bcbd461349f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f299bcd4133a7ef168f576da5225ae0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8ff2ebbf97e694bd83a489b2c52c99 |
publicationDate |
2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2016099-B1 |
titleOfInvention |
Method for the production of antibodies in immunodeficient animal injected with human fetal liver stem cells |
abstract |
The current invention is related to a method for the production of a human monoclonal antibody from an immundeficient non-human animal, said method comprising contacting a newborn immunodeficient non-human animal with a human fetal liver stem cell (FL cell) to generate an immune transplanted non- human animal (reconstituted animal), subsequently contacting said reconstituted animal with an antigen, collecting from said reconstituted animal a human cell producing human antibody against said antigen, and isolating said antibody from said antibody producing cell. |
priorityDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |