Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
2007-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65c5eaf543b2f9d74e9e33caa31c7bf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5fc4ca4866db8f197a871ffb9a7382 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3486349af7fcfd960358be1c14cb1911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79ea404bcd39858deec09bb79aa9940 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ace39b9c94e4094c4226dcf9068137eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da2cdf00d1f354cac197d82506fc3894 |
publicationDate |
2008-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2004837-A2 |
titleOfInvention |
Neutralizing agents for bacterial toxins |
abstract |
Stabilized variable regions of the T cell receptor and methods of making the same using directed evolution through yeast display are provided. In one embodiment, the variable region is variable beta. In one embodiment, the stabilized T cell receptor variable regions have high affinity for a superantigen, such as TSST-1 or SEB. These T cell receptor variable regions are useful as therapeutics. |
priorityDate |
2006-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |