| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fd15d8ebb22202b5cfe2b109cd922c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6298c4c8a9dc65a27deeadf713655d9f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2006-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8277b7e4d973869e763f192113fd0214
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f93700bcb9a13ad973e5697a6906725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_848a7794acfe5b6ca001566817039d62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17645f678df75c4d60227caca231e973
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_971fd768b710c1dd7b8adc54fd8618f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c7ecd1d4e3a3fc4ea59da5cc224d4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02b47e9452c335945065e05f048bef68 |
| publicationDate |
2008-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1993581-A1 |
| titleOfInvention |
Novel use of ubiquitin c-terminal hydrolase-l1 |
| abstract |
The present invention relates to a composition for diagnosing cancer metastasis comprising Ubiquitin C-terminal hydrolase-L1 (UCH-L1), a use of UCH-L1 for diagnosing cancer metastasis and a method for diagnosing cancer metastasis using the same; a composition for suppressing cancer metastasis comprising an inhibitor of UCH-L1, a use of an inhibitor of UCH-L1 for suppressing cancer metastasis and a method of suppressing cancer metastasis using the same; a composition for screening a cancer metastasis inhibitor comprising UCH-L1 protein, a use of UCH-L1 protein for screening a cancer metastasis inhibitor and a method of screening cancer metastasis inhibitor using the same; a composition for screening a cancer metastasis inhibitor comprising UCH-L1 gene, a use of UCH-L1 gene for screening a cancer metastasis inhibitor, a method of screening cancer metastasis inhibitor using the same. UCH-L1 is a key molecule to modulate cell migration including the cancer invasion according to their expression level. Thus, the monoclonal and polyclonal antibodies and the substrate of UCH-L1 can be used for diagnosis of cancer metastasis. Also, the cancer metastasis can be suppressed by inhibiting of the expression of UCH-L1 or activity of the enzyme, thus we can screen and develop an inhibitor of UCH-L1 and use it as an adjuvant drug for anticancer therapy. |
| priorityDate |
2005-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |