| abstract |
Disclosed is a pharmaceutical combination comprising a calcium receptor modulator and a bone resorption inhibitor, wherein the calcium receptor modulator comprises a compound represented by the formula (I):n nwherein the ring A represents a 5- to 7-membered ring which may be substituted; the ring B represents a 5- to 7-membered heterocyclic ring which may be substituted; X 1 represents CR 1 (wherein R 1 represents a hydrogen, a hydrocarbon group which may be substituted, or the like) or the like; X 2 represents N or the like; Y represents C or the like; Ar represents a cyclic group which may be substituted; R represents a hydrocarbon group which may be substituted, or the like; and ----- represents a single bond or a double bond; or a salt thereof or a prodrug of the compound or the salt. |