http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1991674-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4caa77d6ee705e63ba9d4a406c6e5094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b81c3ecc9a3bd192c754216816991d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec7aa9366c4867ba95ac5cd4fbbaec25 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2007-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13033cbea77efff077ea74aaf39c659 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ac63b5f22ab1f3653d098ee96623884 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60ee4f29a4ceb42dfdb09e37693c5d6e |
publicationDate | 2008-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1991674-A1 |
titleOfInvention | Methods and means for metabolic engineering and improved product formation by micro-organisms |
abstract | The invention relates to the field of biochemistry, molecular biology and microbiology. More specific the invention relates to methods and means for metabolic engineering and improved product formation by a filamentous micro-organism or a low G+C gram-positive bacterium. The invention discloses that DasR and DasR binding sites play an important and universal role in the control of gene expression in micro-organisms Based on this finding, the invention provides multiple useful applications, such as a method for regulating the expression of a gene of interest, a method for controlling metabolism, a method for decreasing undesired expression and many more. Moreover, the invention also provides means that can be used to establish said methods: for example a micro-organism in which the DasR binding site in operable linkage with a particular gene has been modified to obtain increased or decreased expression of a protein (being a desired or undesired protein) encoded by said gene. |
priorityDate | 2006-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 173.