http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1989309-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_199450d8e2d705a2b559ce4c32e5dcb3 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 |
filingDate | 2007-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee022ceff9bde10d2466a1e3074f06bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce3b45541cee8163d3ccac472d7e1ace http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f26021fe93b704f3c2a96dcbc51ee5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96b24eb60abb417b84fed760eab53345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90f4eb7b455dd5ec3afcf9cb143ed1ab |
publicationDate | 2011-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1989309-B1 |
titleOfInvention | Genetic modification of homolactic thermophilic bacilli |
abstract | Disclosed herein is a genetic modification of moderately thermophilic Bacillus species that are facultative anaerobic and homolactic. The method includes introducing DNA cloned in a thermosensitive plasmid system containing a pSH71 replicon or a homologue thereof into cells of a moderately thermophilic Bacillus species that is facultative anaerobic and homolactic; culturing the cells on a selective medium at a permissive temperature to select transformed cells; culturing the transformed cells on a selective medium at a non-permissive temperature to select transformed cells capable of growing on the selective medium at the non-permissive temperature. The method can modify the Bacilli for R-lactic acid production, production of other organic acids than lactic acid, alcohol, enzymes, amino acids, and vitamins. The Bacillus species may be modified by replacing the S-lactate dehydrogenase gene by a DNA construct including a DNA sequence encoding R-lactate dehydrogenase. |
priorityDate | 2006-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.