http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1987840-A1

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filingDate 2007-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c007600e68e7bf8decccac02b0cbaee6
publicationDate 2008-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1987840-A1
titleOfInvention Prime-boost vaccine for the protection of equines against viral infection
abstract It has been found that adequate protection against viral infection in equines can be achieved when vaccination with a live viral vaccine (prime) is followed by vaccination with an inactivated vaccine (boost) for the same virus, wherein the two shots are given no longer than 8 weeks apart. n The invention therefore provides a method for vaccination of equines against infection with an equine viral pathogen, wherein an animal is first vaccinated with a (prime) vaccine comprising an attenuated form of the pathogen, followed by a vaccination with a (boost) vaccine comprising the same pathogen in inactivated form, and wherein the boost vaccine is administered no longer than eight weeks after the prime vaccine. n The method of the invention is especially useful for vaccination against viral infections such as infections with EIV and/or EHV-1/EHV-4. n Especially for EIV, it has been found that when equines are vaccinated with such a prime-boost vaccine regimen according to the invention, the equines are protected against clinical signs after a challenge with a virulent EIV.
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Total number of triples: 30.