abstract |
A tissue-selective androgen receptor modulator containing a compound represented by the formulan nwherein Ring A represents an optionally substituted 5- to 8-membered ring, Ring B represents an optionally further substituted 4- to 10-membered ring, Ring C represents an optionally further substituted benzene ring, X 1 represents an optionally substituted carbon atom, X 2 represents an optionally substituted carbon atom, an oxygen atom and the like, W 1 represents a nitrogen atom and the like, Y 11 represents a group represented by the formula CR 2 R 3' (wherein R 2 represents a hydrogen atom, a cyano group, a nitro group and the like, and R 3' represents a bond, a hydrogen atom, a cyano group, a nitro group and the like, respectively), Y 21 represents a group represented by the formula CR 4 R 5' (wherein R 4 represents a hydrogen atom, a cyano group, a nitro group and the like, and R 5' represents a bond, a hydrogen atom, a cyano group, a nitro group and the like, respectively) and the like, R 1 represents an electron-withdrawing group, and the formula n - - - nrepresents a single bond or a double bond, or a salt thereof or a prodrug thereof. |