| abstract |
It is an object of the present invention to provide a gel-forming composition which permits on-site administration and can form a gel exhibiting prescribed strength and sustained drug release, devices for the administration thereof, and a kit for medical use. A gel-forming composition which is composed of the first composition comprising a drug, a first gelling agent represented by the general formula (I) and the like, and the first diluent and the second composition comprising the second gelling agent represented by the general formula (I) and the like and the second diluent; and application devices and kits for medical use, which can hold the gel-forming composition. X 1 - (OCH 2 CH 2 ) n - X 2 (I) wherein X 1 and X 2 are each -R 1 COONHS (wherein R 1 is C 1-7 alkylene), -COR 1 COONHS, -NOCOR 1 -R 2 (wherein R 2 is maleimido), -R 1 NH 2 , -R 1 SH, or -CO 2 PhNO 2 , and n is an integer of 80 to 1000. |