| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-22 |
| filingDate |
2006-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f94c8fad038b1e6cb5e23297a3ca588
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_470a68586efa359b531fedc11fdbc2f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1861322b8e501a78a0a411498a3233fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c45af64b6b4734a4ba51e00f785df4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7878cbf45920268e5d9b06c2c8163760
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47aaabde55a634159d1b09c8cbfe7250
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cf5b0a271651e6fe7f60e0b7fd24da8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a91dd816a300128a23549d9e6d95344d |
| publicationDate |
2008-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1982994-A2 |
| titleOfInvention |
Carbohydrate-mimetic peptides and use thereof in pharmaceutical formulations |
| abstract |
The present invention is related with the pharmaceutical industry and the biotechnology, specifically with vaccine antigens applied against bacterial, viral, cancerous or another origin diseases. Development of pharmaceuticals formulations able to protect or to increase the protective spectrum of already developed vaccines and to extend it against several pathogens, using as target for the immune response, carbohydrates composed of repeated units of (α 2-8) linked N-replaced neuraminic acid. Several peptides were isolated and identified as molecular mimetics of the capsular polysaccharide form serogroup B of Neisseria meningitidis, which is composed of repeated units of (α 2-8) linked N-acetyl neuraminic acid. The immunogenicity of peptides was evaluated in animal biomodels, demonstrating their value as antigens able to induce the production of antibodies able of specifically recognize the bacterium N. meningitidis from serogroup B and of showing bactericidal activity against the same one. The resulting formulations of are applicable in the pharmaceutical industry as vaccine formulations for human use. |
| priorityDate |
2005-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |