| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07addebfc9446dc5a9a77692ebf4dac1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-12 |
| filingDate |
2006-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f094a660725c2854f689e842a8ce06f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db08803cb2c7823cbf4d6aeffb207950
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37a4bfb0995a1cf567755361d49d3017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdffcd0eddcb5dbb41fee30480a83952 |
| publicationDate |
2009-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1981891-B1 |
| titleOfInvention |
The use of oripavine as a starting material for buprenorphine |
| abstract |
There is provided a method for the synthesis of norbuprenorphine, and ultimately buprenorphine, utilizing oripavine as the starting material. Conventional methods of producing buprenorphine utilize thebaine as the starting material, requiring an O-demethylation step, typically a low to moderate yield transformation. The present use of oripavine as a starting material does not require an O-demethylation step, since the oripavine molecule lacks an O-3 methyl group. |
| priorityDate |
2006-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |