Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7dfe6a0b58eafa796df8153e2460c2b8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6435 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2007-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5818dfdd4718c9c2312d5668f024aeb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acd9017b2cd6f76187f0fbdc48f28edc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_957a1bd61f465852ae809af106695c33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8b3fa93049aff12adc863b5481b748a |
publicationDate |
2008-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1981527-A2 |
titleOfInvention |
Thermally-targeted delivery of medicaments, including doxorubicin |
abstract |
Elastin-like polypeptide (ELP) serves as a vector for thermally-targeted delivery of therapeutics, including cytotoxic chemotherapeutic drugs such as doxorubicin. Examples of an ELP-based delivery vehicle can comprise: (1) a cell penetrating peptide, such as a Tat protein, (2) ELP, and (3) the lysosomally degradable glycylphenylalanylleucylglycine (GFLG) spacer and a cysteine residue conjugated to therapeutic such as doxorubicin, or a analog thereof. |
priorityDate |
2006-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |