Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea9c7e01b475ca6ff7142905a7381359 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3843 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
filingDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7c0218b818c361d3b6af261afc177f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09586fc22d956ca72bf4f3356ddc735f |
publicationDate |
2008-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1973554-A2 |
titleOfInvention |
Cartilage repair methods |
abstract |
The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage. |
priorityDate |
2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |