| abstract |
The present invention relates to the use of the compound according to formula (I) Where S is (A) or (B); X is H or F; R<SUP>1</SUP> is H, an acyl group, a C<SUB>1</SUB> - C<SUB>20</SUB> alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester group, a (C)or (D) group; Where Nu is a radical of a biologically active compound such as an anticancer, antihyperproliferative or antiviral compound such that an amino group or hydroxyl group from said biologically active agent forms a phosphate, phosphoramidate, carbonate or urethane group with the adjacent moiety; Each R<SUP>8</SUP> is independently H, or a C<SUB>1</SUB>-C<SUB>20</SUB> alkyl or ether group, preferably H or a C<SUB>1</SUB>-C<SUB>12</SUB> alkyl group; k is 0-12, preferably, 0-2; R<SUP>2</SUP> is H, an acyl group or a C<SUB>1</SUB>-C<SUB>20</SUB> alkyl or ether group; and pharmaceutically acceptable salts, solvates or polymorphs thereof for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states. |