http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1957635-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3a0d6297082cc4413878148c761e49b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6bfd4b61df3f235ef7b241bfa8b06695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a17388bbb17c75e46061872bb0d82a1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 |
| filingDate | 2006-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8df05beb65fbbe1812e336b1cbffcb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee4e7b8e2a9e3be600373b983bf28703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53bdf98ad861c79f5cb568a7f415c76f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b01b973383c8c4128620041cb94411ec |
| publicationDate | 2012-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1957635-B1 |
| titleOfInvention | A method for preservation of human hematopoietic stem or progenitor cells |
| abstract | Maintenance of quiescent hematopoietic stem and progenitor cells (HSPC) in culture without the addition of exogenous growth factors is an important aspect in clinical hematology. A recent report described the ability of Flt3 receptor-interacting lectin (FRIL) in the maintenance of cord blood (CB) derived progenitors in vitro. Since FRIL is a mannose binding lectin we examined the effectiveness of four such lectins of well-characterized specificities on the preservation of HSPC of CB origin. The HSPC preservation activity of lectins was assessed by in vitro colony forming unit (CFU) and long-term culture initiating cell (LTC-IC) assays. It was found that all four lectins had a HSPC preservation activity at least up to 30 days in culture without addition of exogenous growth factors. The results indicate that use of such lectins may provide a cost effective method of HSPC maintenance for clinical use. |
| priorityDate | 2005-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 118.