abstract |
The present invention provides a compound represented by the formula: wherein R1a is a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by-NR6a-CO-(CH2) n -SO2 -optionally halogenated C1-4 alkyl wherein n is an integer of 1 to 4, R6a is a hydrogen atom or a C 1-4 alkyl group, and -(CH2) n - is optionally substituted by C 1-4 alkyl, R3a is a hydrogen atom or a C 1-6 alkyl group, R4a is a halogen atom or a C 1-6 alkyl group, R5a is a halogen atom or a C 1-6 alkyl group, and Xa is a hydrogen atom or a halogen atom, or a salt thereof. The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product. |