| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b3c81bc92f0f06434ec1a01cd0137ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-978 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate |
2006-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4598d4cf05cc57204e97a29e1ccfe3bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c03df45f652f1e402621750c23862b1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_225cb7797e92fb4d611de1a2f22f8e29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dfec29aa2e284e3f5d04995e1e41dec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf49fce240edb36a85804d050c0b7f8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71465095b6862acefa42850c4bf7890f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac727f4334b578493623445e618dbfa0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfff21e641ba8b9e8f39a94d51afe051 |
| publicationDate |
2008-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1954832-A2 |
| titleOfInvention |
Diagnostic methods for pain sensitivity and chronicity and for tetrahydrobiopterin-related disorders |
| abstract |
Disclosed herein are methods for determining whether a subject possesses altered pain sensitivity an altered risk of developing acute or chronic pain, or diagnosing a tetrahydrobiopterin (BH4)-related disorder or a propensity thereto. These methods are based on the discovery of GCHl and KCNSl allelic variants that are associated with altered pain sensitivity and altered risk of developing acute or chronic pain, and the discovery that a GCHl 'pain protective haplotype' is associated with decreased upregulation of BH4 synthesis in treated leukocytes. |
| priorityDate |
2005-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |