http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1951695-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0597f9c318d2aeca86db94711c516383 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-54 |
| filingDate | 2006-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f0b3dc100055d0375301feebfccda0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd4f36694762c781e20348b0aab1c46e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4213f3c99f7fb94f4c48ba51c6460337 |
| publicationDate | 2008-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1951695-A1 |
| titleOfInvention | CATALYZED PROCESS OF MAKING C-5-SUBSTITUTED HETEROCYCLIC INHIBITORS OF 11ß-HYDROXY STEROID DEHYDROGENASE TYPE 1 |
| abstract | The invention provides a process for preparing 11 ß-hydroxy steroid dehydrogenase type 1 inhibitors of formula (II) via a catalyzed reaction between a compound of formula (I) and a compound of formula R2LG in the presence of base: where R1, R2, X, Y, and LG are described in the specification. Exemplary catalysts contain palladium and one or more phosphine ligands. The process can be performed in a stereoselective manner to give enantiomerically enriched products. |
| priorityDate | 2005-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 580.