| abstract |
The invention relates to compounds of the general formulae (1) and (2) A - B - D - B' - A' (1) and A - B - D - E (2), in which A and A' may be identical or different and are the radical (I) in which X is S, O, CH<SUB>2</SUB>, CH<SUB>2</SUB>CH<SUB>2</SUB>, CH<SUB>2</SUB>O or CH<SUB>2</SUB>NH, and Y is H or CN, and * designates a chiral carbon atom, preferably in the S or L configuration; B and B' may be identical or different and are an O-, N- or S-containing or non-O-, N- or S-containing, unsubstituted or substituted, unbranched or branched alkylene radical, cycloalkylene radical, aralkylene radical, heterocycloalkylene radical, heteroarylalkylene radical, arylamidoalkylene radical, heteroarylamidoalkylene radical, unsubstituted or mono- or polysubstituted arylene radical or heteroarylene radical having one or more five-, six- or seven-membered ring(s); D is -S-S- or -Se-Se-; and E is the group -CH<SUB>2</SUB>-CH(NH<SUB>2</SUB>)-R<SUP>9</SUP> or -CH<SUB>2</SUB>-*CH(NH<SUB>2</SUB>)-R<SUP>9</SUP>in which R<SUP>9</SUP> is an O-, N- or S-containing or non-O-, N- or S-containing, unsubstituted or substituted, unbranched or branched alkyl radical, cycloalkyl radical, aralkyl radical, heterocycloalkyl radical, heteroarylalkyl radical, arylamidoalkyl radical, heteroarylamidoalkyl radical, unsubstituted or mono- or polysubstituted aryl radical or heteroaryl radical having one or more five-, six- or seven-membered rings and * designates a chiral carbon atom preferably in the S or L configuration; or the acid addition salts thereof with organic and/or inorganic acids; and the use of the compounds of the general formulae (1) and (2) in medicine. |