http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1945621-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2836e9565acd2397f87e19c95dbfefe |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-66 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47 |
| filingDate | 2006-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2cc1e821977044b69bcdc1aaaaff062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec31c0d0c28591600691a01a62849c58 |
| publicationDate | 2009-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1945621-B1 |
| titleOfInvention | Process to prepare amino acid derivatives |
| abstract | The present invention comprises a novel multi-step process to a specific amino acid derivative (1) from (4-hydroxymethyl)benzaldehyde including the key steps of: (i) asymmetric hydrogenation, thereby avoiding yield losses associated with the resolution approach and (ii) introduction of the cis-2,6-dimethylpiperidine sub-unit by JV-alkylation, thereby avoiding a problematic reductive animation step that is prone to side reactions. In one aspect, the present invention comprises a synthetic route in which step (i) precedes step (ii). In another aspect of the invention, step (ii) precedes step (i) (I). |
| priorityDate | 2005-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 165.