http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1943209-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66996dcf2dc59f595b8c0584986d50b3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-313 |
| filingDate | 2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76680a91d3f70b2367b0cfa26faac21a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48b0e728b691460645b4f81a3f8c229a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58a04fe9e3cbee5a3e79c1c1de2b7177 |
| publicationDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1943209-B1 |
| titleOfInvention | A process for preparing beta-ketoester compounds |
| abstract | The present invention relates to a process for preparing a beta-keto ester compound of formula (1) , which is an intermediate for the synthesis of quinolone antibiotics. Particularly, the present invention is characterized by the reaction of an organo nitrile compound with a salt of mono-alkyl malonate in the presence of metal salt, and so the reaction is easy to control due to its endothermic nature, and is devoid of lachrymatory reagents with excellent reproducibility. Subsequent in situ hydrolysis in the presence of aqueous acid solution provided the compound of formula (1). |
| priorityDate | 2005-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.