http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1940793-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92205428e0fbc3b39a4bab31a94b5ada |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f0de2b3ce75568cf595b1ff5d7040d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7138f6a9b451f4ede0aaab48ddb7410a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba7b778d4d6311571650fe4cec5be92c |
| publicationDate | 2008-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1940793-A2 |
| titleOfInvention | A process for the preparation of montelukast |
| abstract | The present invention relates to a process for the preparation of Montelukast or a salt thereof comprises, i) condensing Methyl -2-[3-[3-(2-(7 - chloroquinolin -2-yl) ethenyl] phenyl] -3 -chloro propyljbenzoate obtained above with l-(mercaptomethyl) cyclopropane acetic acid in presence of alkali carbonates such as Cesium Carbonate, followed by salification with organic amine ii) neutralizing the organic amine salt as obtained above with organic/inorganic acid followed by reaction with methylmagnesium chloride in the presence of Cerium Chloride followed by treatment with organic base yields montelukast amine salt iii) converting the montelukast amine salt to Montelukast Free acid iv) saltification of Montelukast free acid with Sodium hydroxide affords Montelukast Sodium. |
| priorityDate | 2005-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 176.