Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac2c17e532220d91aca9a28ef60f178b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-665 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 |
filingDate |
2003-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e6c8d0d0fe8b8dcec0af3fab045111f |
publicationDate |
2008-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1927858-A1 |
titleOfInvention |
Conformationally constrained peptides that bind the ORL-1 receptor |
abstract |
The present invention relates to peptidomimetic ORL-1 receptor ligands containing certain conformationally constrained amino acids that favor alpha-helix or extended beta-strand conformations. Preferably, the ORL-1 receptor ligands of the present invention have one or more residues in an "address" segment to promote alphahelix formation. The ligands of the present invention include ORL-1 receptor agonists that may be used as analgesics to treat pain in a patient in need of such treatment, and also may be used to treat anxiety, addiction, withdrawal and drug tolerance, as well as to enhance memory and learning. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10702540-B2 |
priorityDate |
2002-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |