| abstract |
The present invention relates to a new use of opioid receptor antagonists. More particularly, the present invention relates to the use of opioid receptor antagonists for the manufacture of topical compositions for suppression of melanin formation in the human skin; to topical, particularly cosmetic, compositions for suppression of melanin formation in the human skin comprising an opioid receptor antagonist; and to a method of lightening human skin and/or treatment of pigmentation disorders which comprises topically administering an effective amount of an opioid receptor antagonist to the appropriate skin area of a person in need of such treatment. |