http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1918718-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 |
| filingDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1918718-A1 |
| titleOfInvention | Methods and devices for electrochemical determination of factor Xa inhibitors in blood samples |
| abstract | The invention relates to methods and devices, in particular test elements such as test strips, for the determination of factor Xa inhibitors, in particular of heparins and fractionated or low molecular weight heparins and direct FXa inhibitors, in blood samples, which are characterized in that in a first step, a sample of blood to be examined with a detection reagent which contains at least one thrombin substrate which consists of a peptide residue which can be cleaved off by thrombin and which is linked amidically via the carboxyl end to an electrogenic substance, and brought into contact with a known amount of factor Xa is then, in a second step, the amount or activity of the electrogenic substance, which is cleaved by the factor Xa-mediated thrombin activation of the thrombin substrate, and / or their time course is determined as a measurement signal with electrochemical methods, and finally in a third S chritt on the basis of this measurement signal, the amount of the factor Xa inhibitor in the sample of the blood to be examined, or a correlating measure, in particular a correlating coagulation time is determined. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2471945-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889370-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2471946-A1 |
| priorityDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.