| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed28726de9f916f355f8adc331e736b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-149 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-10 |
| filingDate |
1996-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a3fc24b936ad8295662cc73648856b3 |
| publicationDate |
2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1914238-A2 |
| titleOfInvention |
Methods for measuring physical characteristics of nucleic acids by microscope imaging |
| abstract |
The present invention conerns a method of preparing an individual elongated nucleic acid molecule fixed onto a solid planar surface, comprising depositing the nucleic acid molecule onto a planar glass surface coated with a positively charged substance that increases the electrostatic interaction between the nucleic acid molecule and the surface, and which reproducibly elongates and fixes the nucleic acid molecule to the surface such that the single nucleic acid spans 20% to 60% of its curvilinear contour length, wherein the charge density is sufficient to maintain the nucleic acid molecule in an elongated state while allowing for a small degree of relaxation, and wherein the small degree of relaxation yields a gap of 0.5 µm to 5.0 µm when the elongated nucleic acid molecule is cut, and wherein the elongated fixed nucleic acid molecule remains individually manipulable and accessible for enzymatic and/or hybridization reactions. |
| priorityDate |
1995-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |