http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1907544-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f31ed47dc5646303450892cf69804905 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate | 2006-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_487fc15ef49e4a57d5c5add590a3173a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d825572e400cd2dec3fff1354305c2c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_547afd395f859bd1a8af86cf4943352b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c7a4cba9993068cd0034931d925cb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7ac1b9fe9077aa67078a0cc36b6dd26 |
publicationDate | 2008-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1907544-A1 |
titleOfInvention | Membrane-translocating peptides |
abstract | A method is provided for selecting membrane-translocating peptides (MTPs) from a peptide display library that are capable of crossing or penetrating a lipid membrane. A plurality of nucleic acid constructs that encode displayed peptides are expressed, resulting in the formation of a plurality of nucleic acid-peptide complexes, each complex comprising at least one displayed peptide associated with the corresponding nucleic acid construct encoding the displayed peptide; the complexes are exposed to a population of membrane-encapsulated compartments, allowing a translocating reaction to occur; complexes that remain unassociated with the membrane are removed; optionally complexes that are associated with the membrane are removed; and internalised nucleic acid-peptide complexes are recovered. The membrane-encapsulated compartments may be artificial vesicles such as liposomes, or populations of one or more cell types. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3014270-A4 |
priorityDate | 2005-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 149.