| abstract |
A controlled release solid pharmaceutical formulation comprising: na core comprising a first composition comprising a physical mixture of a therapeutic agent and at least one sulfoalkyl ether cyclodextrin, wherein a major portion of the therapeutic agent is not complexed with the sulfoalkyl ether cyclodextrin; and na coating surrounding said core and consisting of a film forming agent; nwherein, said therapeutic agent of the first composition is released from the core at a controlled rate in the absence of a pore forming agent in the coating. |