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publicationDate 2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1892301-A1
titleOfInvention Method for evaluation of compound using rsk1
abstract A method for evaluation of a compound comprising the steps of introducing an RSK1 gene into a cell to prepare a cell capable of expressing RSK1, contacting a compound to be evaluated with the cell, and detecting the specific binding of the compound to RSK1; and a compound given by the method. The compound can be used as a potentiator or cisplatin. The method enables to find a gene which acts specifically on a cell of cancer induced by the abnormality of p53 or enhanced MAPK pathway and to evaluate a compound by using the gene.
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