Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47fcc3c016fb5d1a627791e61d66305a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2006-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3dc0e777adea99311b526e10b781573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1847bcbb7b3872b90c72aabbc82a51c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_857232dd66e48502f944f78a8c519f1f |
publicationDate |
2008-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1887860-A2 |
titleOfInvention |
Murine stem cells and applications thereof |
abstract |
The invention relates to animal solid tumour models which comprise a transgenic non-human mammal containing in its genome a DNA construct that comprises a gene created and/or activated by a genetic anomaly associated with human cancer operatively bound to a promoter that directs the expression of the gene in Scal+ cells. The invention also relates to stem cells capable of specifically expressing in stem cells human genetic anomalies associated with human pathologies. Applications of these models and stem cells, such as diagnostic, therapeutic and prophylactic applications for human diseases, and products and methods are provided. |
priorityDate |
2005-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |