http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1886666-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
filingDate 2007-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e3096286227b50f6752a6852bba2cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21b3b86ae00e03b4bc21cdadf364b1d2
publicationDate 2008-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1886666-A1
titleOfInvention Method for manufacturing a composite made of oligo- or polynucleotide and hydrophobic biodegradable polymers and composite created according to this method
abstract The invention relates inter alia to a process for the preparation of a composite of oligo- or polynucleotides and hydrophobic biodegradable polymers. The method comprises the steps: (i) preparing an aqueous solution of a water-soluble polyethylene glycol; (ii) adding an aqueous, optionally buffered solution of oligo- or polynucleotides to the aqueous solution of step (i); (iii) freezing the aqueous solution of step (ii) and then freeze-drying the frozen solution to obtain a freeze-dried substrate; (iv) providing a solution of the hydrophobic biodegradable polymer in an organic solvent; (v) adding the substrate obtained after step (iv) to dissolve the polymer; and (vi) removing the organic solvent to obtain the composite.
priorityDate 2006-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.