http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1884239-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a89514464d02d75ef2065a449fb0e617 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 |
| filingDate | 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23025d069f8eb46b4c5062025dba493 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07da0741138df0e3014c2ad3d1f1e2a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5987d61cde054bd56381b129da569360 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73ec9e6ff1dbde305859856e58a1adb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b58e7dc398da79c0f3a72dafbc9d41fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d3b53f734cc3d4e145722e040c4c257 |
| publicationDate | 2008-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1884239-A1 |
| titleOfInvention | Annellated pyrrole compounds for cancer management |
| abstract | The present invention relates to the use of annellated pyrrole compounds and in particular ML3000 (licofelone)n nsalts or derivatives thereof, for cancer management, and in general to the use of a compound of Formula (I):n nwherein the variables have the meanings given in the present description, nfor the prevention and/or treatment of neoplasia, in particular neoplasia selected from the group consisting of papilloma, carcinoma, adenoma and adenocarcinoma, e. g. human airway or colorectal carcinoma, preferably fast-growing, multidrug resistant and/or COX-2 negative neoplasia. n The invention further relates to pharmaceutical compositions for the aforesaid purposes, comprising annellated pyrrole compounds and in particular ML3000 (licofelone), optical isomers, salts or derivatives thereof, as well as to a method of treating and/or preventing neoplasia and/or restoring the ability to undergo apoptosis in a cell having lost the same. n This treatment ameliorates, diminishes, actively treats, reverses or prevents any disease related to insufficient apoptosis, in particular neoplasia, and it may be combined with irradiation, heating and treatment with a cytotoxic agent for preventive and/or curative purposes. |
| priorityDate | 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1189.