http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1880228-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54326 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-465 |
filingDate | 2006-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_824e780cca974e92e3ec148690cfd700 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25ca83c186a8327544da3011a3ac94c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_146246807ee385d7b33251e930ee65e1 |
publicationDate | 2008-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1880228-A2 |
titleOfInvention | Water relaxation-based sensors |
abstract | This invention relates to magnetic resonance-based sensors and related methods . More specifically, the invention relates to a sensor based on magnetic resonance for detecting the presence of an analyte in a sample solution. The sensor comprises magnetic nanoparticles linked to a moiety upon which the analyte can reversibly bind, the nanoparticles being confined in a chamber with semipermeable walls which are impermeable to the nanoparticles but permeable to the analyte. Upon binding of the analyte to the nanoparticles, the latter aggregate which can be deteceted by a change in the T2 relaxation time of the sample solution within the chamber (magnetic relaxation switch) . The analyte may be a carbohydrate such as glucose, an antibody, an amino acid, a nucleic acid, an oligonucleotide, a therapeutic agent, a peptide, a protein, etc. The sensor may be used as an assay and may be read out using MRS or MRI, e.g. of well plates for high throughput anaylsis . |
priorityDate | 2005-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.