abstract |
The present invention relates to the preparation of an equivalent epidermis capable of pigmentation comprising cells derived from the differentiation of the cells of the matrix, as well as to the equivalent epidermis obtained.n n n The present invention also relates to a reconstructed skin capable of pigmentation and optionally comprising hair follicles, comprising said epidermal equivalent, its preparation process and its use for evaluating the effect of topical cosmetic, pharmaceutical or dermatological products.n n n The reconstructed skin according to the invention may also be used for the preparation of grafts intended to be transplanted on mammals, more particularly on human patients such as burn victims. |