| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92d71a3e23389a3bca747290fc6464cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 |
| filingDate |
2006-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77cd07d61a6d387858f35b10534f0d7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6915aaf39bf4c805c6f748fa2c9b3da9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22aa5ca71a129a68514ec06f230b33a5 |
| publicationDate |
2011-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1878745-B1 |
| titleOfInvention |
Humanin receptor or humanin-like polypeptide receptor |
| abstract |
It is aimed at searching for a receptor based on the dada in the HN signal pathway and finding out a humanin receptor or a humanin-like polypeptide receptor (HNR)to thereby clarify the mechanism of promoting or inhibiting the intracellular signaling exerting, for example, the nerve protecting activity of HN; specifying a compound relating thereto; establishing a method of screening an HNR agonist and an HNR antagonist; utilizing the thus screened compounds in developing a remedy for a neurodegenerative disease, in particular, Alzheimer’s disease; providing an assay system for Alzheimer’s disease nerve cell death; and providing a method of the forced expression of HNR gene and a method of knock-outing a gene in a cell. Namely, a humanin receptor or a humanin-like polypeptide receptor containing at least two proteins selected from the group consisting of gp130 or a partial peptide thereof, CNTF-R and WSX-1. |
| priorityDate |
2005-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |