| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96817048d35cb5af7e02635662d66598 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F222-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08K5-0091 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F23-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L35-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-00 |
| filingDate |
2006-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4f4da58523d54ba0399e38d958315c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0c015ce98a8932e23cf6053dd2973cc |
| publicationDate |
2011-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1873204-B1 |
| titleOfInvention |
Polymeric pharmaceutical agent for treatment of cancer and process for production of the same |
| abstract |
[PROBLEMS] To provide a polymeric pharmaceutical agent which can contain the active ingredient in a larger amount, which can be highly accumulated in tumor tissues, and which has a molecular size that is large enough not to undergo the renal excretion. [MEANS FOR SOLVING PROBLEMS] The polymeric pharmaceutical agent capable of containing the active ingredient in a large amount can be produced by forming a styrene-maleic acid copolymer (SMA) micelle complex comprising a metalloporphyrin derivative (e.g., zinc protoporphyrin) and an SMA conjugated to each other via non-covalent bonding. This SMA micelle complex can be produced by reacting a metalloporphyrin derivative with an SMA in the absence of a condensing agent under alkaline conditions, solubilizing the resulting product, adjusting the reaction to pH 6 to 8, and collecting a polymeric micelle complex component having the active ingredient contained therein by a procedure for separating a polymeric component. |
| priorityDate |
2005-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |