| abstract |
The invention relates to novel methods of preventing, treating, or ameliorating medical conditions, including cancer, drug resistance, and parasite infections such as malaria, by administering compounds that are capable of inhibiting glutathione-S-transferase, as well as to the use of said compounds for preparing pharmaceutical compositions for preventing, treating, or ameliorating said medical conditions. Furthermore, the invention relates to novel GST inhibitor compounds and pharmaceutical compositions comprising said GST inhibitors, optionally comprising further compounds known to be effective in treating said medical conditions. |