Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_995c71109762882f3cc26e74d8d61acf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c4ceeea48f9a6c3a30a1250206b73e7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-008 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 |
filingDate |
2006-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd5c0dd88d55a2977f928b60adb15ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b00d81711bec9ce61177ef46b5b6ef59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2d67442f48e0321a00019f875c8a4a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db6b012180a73b83d59160df59eab733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01a334ca8ba501ad3d69ce1fab83553f |
publicationDate |
2007-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1858908-A2 |
titleOfInvention |
Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity |
abstract |
Semi-synthetic glycopeptides that have antibacterial activity are based on modifications of a rearranged vancomycin or desmethyl-vancomycin scaffold, in particular, alkylation or acylation of the amino substituent on the amino-substituted sugar moiety on this scaffold with certain acyl groups; and/or conversion of the acid moiety on the macrocyclic ring of this scaffolds to certain substituted amides. Also provided are methods for synthesis of the compounds, pharmaceutical compositions containing the compounds, and methods of use of the compounds for the treatment and/or prophylaxis of diseases, especially bacterial infections. |
priorityDate |
2005-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |