http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1854488-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d7b40cb658a945bd0a6c76a56ed26ac |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate | 2000-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0911164c9c56cd33e7ea5a0335f8f61b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4245522159bdede777bd49ecbca0ba2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe5f14498c5d147210061af6cab546bd |
publicationDate | 2007-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1854488-A1 |
titleOfInvention | Methods for treatment of hyperproliferative diseases using human MDA-7 |
abstract | The present invention relates to gene therapy methods for the treatment of human disease. More specifically, the invention is directed, in one embodiment, to methods for treating a subject with a hyperproliferative disease. In another embodiment, an adenoviral expression construct comprising a nucleic acid encoding a human MDA-7 protein under the control of a promoter operable in eukaryotic cells is administered to the patient with a hyperproliferative disease. The present invention thus provides a gene therapy for treating hyperproliferative disease by elevating the expression of MDA-7 resulting in inhibition of cell growth and induction of apoptosis in hyperproliferative cells. |
priorityDate | 1999-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 2366.